Updatedon January 18, 2023. Medically reviewed by Marissa Sansone, MD. Taking Tylenol (acetaminophen) with anti-inflammatory drugs like Aleve (naproxen) or Advil (ibuprofen) is generally considered safe, as long as you don't exceed recommended dosages. Acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) have different compositions Thedrug can be applied topically as a cream or gel, or taken orally in tablet form. It can also be prescribed by a doctor to be used rectally (as a suppository). What dosage should you take? The typical dosage for adults is 25 to 50mg three times a day for short-term pain management. You should not exceed a maximum total dose of 150mg per day. Breastfeedingisn't recommended if you're taking diclofenac. X. For Seniors. Seniors are at higher risk for stomach problems, bleeding, water retention, and other side effects from diclofenac diclofenac A total of 419 drugs are known to interact with diclofenac . Diclofenac is in the drug class Nonsteroidal anti-inflammatory drugs . Diclofenac is used to treat the following conditions: Ankylosing Spondylitis. Aseptic Necrosis. Back Pain. .

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